South San Diego Vacations from $314

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Your South San Diego Vacation

Leave all the planning to us with a South San Diego vacation package. With everything arranged before you jet off, all you'll have to do is relax and enjoy this destination's wonders to the fullest. A trip to South San Diego wouldn't be complete without spending a day or two in Chula Vista. This city is among the leading places to visit here. From the moment you book your South San Diego vacation to when you get back home, Expedia will be with you every step of the way.

The Latest South San Diego vacation packages

Price found within the past 48 hours. Click for updated prices.
Guesthouse Hotel at La Valle

Guesthouse Hotel at La Valle

Save 100% on your flight
$314
per person
Dec 11 - Dec 13
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (269 reviews)
No food service other than a funky cafe with one young lady being worked to death. 2 coffees in the room for 2 people. They need to elevate their game.

Reviewed on Oct 22, 2026

Fairmont Grand Del Mar

Fairmont Grand Del Mar

Carmel Valley
$883
per person
Nov 23 - Nov 26
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.6/10 Exceptional! (1,002 reviews)
Restaurant inside hotel was horrible don’t even try it

Reviewed on Oct 19, 2026

Pantai Inn

Pantai Inn

Village of La Jolla
Save 100% on your flight
$905
per person
Dec 3 - Dec 6
found 12 hours ago
Roundtrip flight included
New York (JFK) to San Diego (SAN)
9.4/10 Exceptional! (1,008 reviews)
Murrieta Hot Springs Resort

Murrieta Hot Springs Resort

Murrieta Hot Springs
$460
per person
Dec 14 - Dec 17
found 12 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (652 reviews)
This resort is beautiful but unfortunately the service is NOT. I Stayed here for 4 days . They don’t do house keeping unless you ask and when I asked , the my said they are short staffed . That shouldn’t be the guests problem if the resort does not have enough workers to give five star services . Everything else was really nice.

Reviewed on Oct 21, 2026

Coronado Beach Resort

Coronado Beach Resort

Historic Downtown Coronado
$449
per person
Dec 7 - Dec 11
found 6 hours ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9/10 Wonderful! (838 reviews)
Nice property. I'd do it again!

Reviewed on Oct 23, 2026

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Where to stay in South San Diego

Find the best South San Diego areas and neighborhoods for the activities you enjoy most. Learn more about South San Diego
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Egger Highlands

Though Egger Highlands might not have many top sights, you can venture to the surrounding area to see attractions like Imperial Beach and Chula Vista Center.

A marina with boats docked, a city skyline with high-rise buildings, and a sunset with pink and orange clouds.

Otay Mesa West

Even though there aren't top sights in Otay Mesa West, you can explore the larger area and take in top sights like San Ysidro Border Crossing. Jump on the metro at Iris Avenue Trolley Station to see more of the city.

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Seacoast

While there might not be top attractions in Seacoast, you can explore the larger area and discover places like Imperial Beach and Silver Strand State Beach.

A lake with mountains in the background and a single tree in the foreground.

Otay

Live music, theaters, and restaurants are some highlights of Otay. You might stop by San Ysidro Border Crossing or Sesame Place San Diego while you're in the area.

A large building with a dome, surrounded by palm trees and a reflecting pond with ducks.

Nestor

While Nestor isn't home to many top sights, San Ysidro Border Crossing and Imperial Beach are some notable places to visit nearby.

Stay near popular South San Diego attractions

The exterior of the Mattress Firm Amphitheatre with palm trees and a clear sky.

North Island Credit Union Amphitheatre

7.6/10 (374 reviews)
You can enjoy a show at North Island Credit Union Amphitheatre on your trip to Chula Vista. Experience the acclaimed theater scene and great live music in this walkable area.
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A pier extending into the ocean with waves crashing against it.

Imperial Beach

8.6/10 (278 reviews)
Why not spend a lazy afternoon at Imperial Beach during your trip to Imperial Beach? Wander the beautiful beaches in this romantic area.
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A sandy beach with large rocks in the foreground and a sailboat on the water.
Photo by Christine Buggs

Chula Vista Bayside Park

10.0/10 (1 review)
Chula Vista Bayside Park is just one of the places to see in Chula Vista, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or visit the shops in this family-friendly area.
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Chula Vista Center

8.0/10 (435 reviews)
During your visit to Chula Vista, you can do some window-shopping at Chula Vista Center. Wander the beautiful beaches and waterfront in this family-friendly area.
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Chula Vista Elite Athlete Training Center

7.4/10 (223 reviews)
Catch an event at Chula Vista Elite Athlete Training Center, and enjoy other activities in Chula Vista such as biking. Amble around this family-friendly area's beautiful beaches or experience its great live music.
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Otay Ranch Town Center

You can do some window-shopping at Otay Ranch Town Center during your trip to Chula Vista.
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Safe Harbor Bayfront Marina

Explore the waterfront in Chula Vista with a trip to Safe Harbor Bayfront Marina. Check out the shops and top-notch restaurants in this family-friendly area.
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What to do in South San Diego

San Diego Whale Watching & Dolphin Cruise

San Diego Whale Watching & Dolphin Cruise

$71
per adult
88% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

$11
per adult
San Diego: Luggage Storage in Marina
See all activities in South San Diego

South San Diego Hotel Deals

Wyndham San Diego Bayside

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
$211 total
Oct 26 - Oct 27
Total with taxes and fees
Wyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$194 nightly
$225 total
Nov 24 - Nov 25
Total with taxes and fees
Hard Rock Hotel San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

1404 Vacation Rd San Diego CA
$261 nightly
$300 total
Oct 25 - Oct 26
Total with taxes and fees
Paradise Point Resort & Spa
See all 8,036 properties in South San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best South San Diego Vacation Packages

South San Diego Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Diego Intl. Airport (SAN)

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.