South San Diego Vacation Packages 2026 from $561

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Your South San Diego Vacation

Leave all the planning to us with a South San Diego vacation package. With everything arranged before you jet off, all you'll have to do is relax and enjoy this destination's wonders to the fullest. A trip to South San Diego wouldn't be complete without spending a day or two in Chula Vista. This city is among the leading places to visit here. From the moment you book your South San Diego vacation to when you get back home, Expedia will be with you every step of the way.

The Latest South San Diego vacation packages

Price found within the past 48 hours. Click for updated prices.

Hotel Z

Downtown San Diego

Save 100% on your flight

$561

per person

Jan 14 - Jan 18

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to San Diego (SAN)

9.2/10 Wonderful! (1,191 reviews)

My stay was great. I stayed with my service animal for a business trip. They have cleaned up downtown and it is so safe to walk around now. Especially, in morning and at night. Also, they accidentally charged me a pet fee and I called them and they instantly refunded it. The front desk has been very helpful and made our stay very smooth. The A/C worked great, the bed was comfortable and it was quiet. I did not park a car, but the valet was in front and it seemed easy. My business partner picked me up and he was easily able to wait out front for me to come down. The room was clean as well as the bathroom. They are doing some construction in the elevator as well as the left side of the hotel, but they manage it well and it isn't loud. Would stay there again. It is so nicely located.

Reviewed on Oct 22, 2026

Pantai Inn

Village of La Jolla

Save 100% on your flight

$878

per person

Dec 6 - Dec 9

found 1 day ago

Roundtrip flight included

Boston (BOS) to San Diego (SAN)

9.4/10 Exceptional! (1,008 reviews)

The Sofia Hotel

Downtown San Diego

$1,063

per person

Dec 28 - Jan 4

found 2 days ago

Roundtrip flight included

Boston (BOS) to San Diego (SAN)

8.8/10 Excellent! (2,743 reviews)

Glorietta Bay Inn Coronado Island

Historic Downtown Coronado

Save 100% on your flight

$1,100

per person

Nov 30 - Dec 7

found 1 day ago

Roundtrip flight included

Boston (BOS) to San Diego (SAN)

8.6/10 Excellent! (1,012 reviews)

Urban Boutique Hotel

Downtown San Diego

$764

per person

Jan 9 - Jan 16

found 17 hours ago

Roundtrip non-stop flight included

Boston (BOS) to San Diego (SAN)

8.6/10 Excellent! (1,232 reviews)

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Where to stay in South San Diego

Find the best South San Diego areas and neighborhoods for the activities you enjoy most. Learn more about South San Diego

Egger Highlands

Though Egger Highlands might not have many top sights, you can venture to the surrounding area to see attractions like Imperial Beach and Chula Vista Center.

A marina with boats docked, a city skyline with high-rise buildings, and a sunset with pink and orange clouds.

Otay Mesa West

Even though there aren't top sights in Otay Mesa West, you can explore the larger area and take in top sights like San Ysidro Border Crossing. Jump on the metro at Iris Avenue Trolley Station to see more of the city.

Seacoast

While there might not be top attractions in Seacoast, you can explore the larger area and discover places like Imperial Beach and Silver Strand State Beach.

A lake with mountains in the background and a single tree in the foreground.

Otay

Live music, theaters, and restaurants are some highlights of Otay. You might stop by San Ysidro Border Crossing or Sesame Place San Diego while you're in the area.

A large building with a dome, surrounded by palm trees and a reflecting pond with ducks.

Nestor

While Nestor isn't home to many top sights, San Ysidro Border Crossing and Imperial Beach are some notable places to visit nearby.

Stay near popular South San Diego attractions

The exterior of the Mattress Firm Amphitheatre with palm trees and a clear sky.

North Island Credit Union Amphitheatre

7.6/10 (374 reviews)

You can enjoy a show at North Island Credit Union Amphitheatre on your trip to Chula Vista. Experience the acclaimed theater scene and great live music in this walkable area.

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A pier extending into the ocean with waves crashing against it.

Imperial Beach

8.6/10 (278 reviews)

Why not spend a lazy afternoon at Imperial Beach during your trip to Imperial Beach? Wander the beautiful beaches in this romantic area.

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A sandy beach with large rocks in the foreground and a sailboat on the water.

Chula Vista Bayside Park

10.0/10 (1 review)

Chula Vista Bayside Park is just one of the places to see in Chula Vista, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or visit the shops in this family-friendly area.

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Chula Vista Center

8.0/10 (435 reviews)

During your visit to Chula Vista, you can do some window-shopping at Chula Vista Center. Wander the beautiful beaches and waterfront in this family-friendly area.

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Chula Vista Elite Athlete Training Center

7.4/10 (223 reviews)

Catch an event at Chula Vista Elite Athlete Training Center, and enjoy other activities in Chula Vista such as biking. Amble around this family-friendly area's beautiful beaches or experience its great live music.

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Otay Ranch Town Center

You can do some window-shopping at Otay Ranch Town Center during your trip to Chula Vista.

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Safe Harbor Bayfront Marina

Explore the waterfront in Chula Vista with a trip to Safe Harbor Bayfront Marina. Check out the shops and top-notch restaurants in this family-friendly area.

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What to do in South San Diego

San Diego Whale Watching & Dolphin Cruise

$71

per adult

88% of travellers recommend

San Diego: Luggage Storage in Marina

$11

per adult

See all activities in South San Diego

South San Diego Hotel Deals

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA

Fully refundableReserve now, pay when you stay

$182 nightly

$211 total

Oct 26 - Oct 27

Total with taxes and fees

8.4/10 Very Good! (6,349 reviews)

"This is the second time I have stayed there and the rooms are really nice and the view is amazing."

Reviewed on Oct 23, 2026

Hard Rock Hotel San Diego

207 5th Ave San Diego CA

Fully refundableReserve now, pay when you stay

$193 nightly

$224 total

Nov 23 - Nov 24

Total with taxes and fees

9/10 Wonderful! (4,551 reviews)

"Had an excellent stay will be back again!"

Reviewed on Oct 23, 2026

Paradise Point Resort & Spa

1404 Vacation Rd San Diego CA

$285 nightly

$328 total

Oct 25 - Oct 26

Total with taxes and fees

See all 8,036 properties in South San Diego

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.